Invitamos a leer el artículo: “Hydrogen sulfide prevents the vascular dysfunction induced by severe traumatic brain injury in rats by reducing reactive oxygen species and modulating eNOS and H2S-synthesizing enzyme expression”, en la que colaboraron el Doctora Araceli Sánchez López, la Doctora Luisa Rocha y el Doctor David Centurión, Investigadores de Cinvestav Sede Sur

Autores: Félix I. López Preza, Saúl Huerta de la Cruz, Cindy Santiago Castaneda, Diana L. Silva Velasco, Jesús H. Beltrán Ornelas, Jorge Tapia-Martínez, Araceli Sánchez López, Luisa Rocha, David Centurión

Felicitamos al estudiantado y profesorado que contribuyeron en esta investigación por su arduo trabajo.

Abstract: Animals underweministration does not prevent the body weight loss but slightly imnt a lateral fluid percussion injury, and the hemodynamic variables were measured in vivo by plethysmograph method. The vascular function in vitro, the ROS levels by the DCFH-DA method and the expression of H2S-synthesizing enzymes and eNOS by Western blot were measured in isolated thoracic aortas at day 7 post-TBI. The effect of LNAME on NaHS-induced effects in vascular function was evaluated. Brain water content was determined 7 days after trauma induction. Body weight was recorded throughout the experimental protocol, whereas the sensorimotor function was evaluated using the neuroscore test at days − 1 (basal), 2, and 7 after the TBI induction.

Keywords: Hydrogen sulfide, H2S-synthesizing enzymes, Vascular dysfunction, Traumatic brain injury, Endothelial function